Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

Ma et al. perform single-cell RNA sequencing of primary liver cancers and find heterogeneity in malignant cells and in the tumor microenvironment, the degree of which negatively associates with patient prognosis. They demonstrate that VEGF expression is linked to tumor diversity and T cell dysfunction.

from Cancer Cell https://ift.tt/2oPHIYe
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