Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors

Mazrooei et al. show that somatic SNVs are enriched in cistromes of master transcription regulators in prostate cancers but not in adjacent normal tissues. Few SNVs alter CREs but collectively target essential transcription regulators.

from Cancer Cell https://ift.tt/33TyU3y