Leruste et al. find that, despite their low mutation burden, rhabdoid tumors have a high rate of infiltration by T cells and myeloid cells, and the immunogenicity is linked to endogenous retrovirus expression. Immune checkpoint blockade induces tumor regression in a rhabdoid tumor mouse model.
from Cancer Cell https://ift.tt/2WWqZ2K
from Cancer Cell https://ift.tt/2WWqZ2K