Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia

Using single-cell analysis of B cell acute lymphoblastic leukemia (B-ALL) patient samples, Witkowski et al. show that the frequency of non-classical monocytes predicts patient survival. Depletion of these monocytes improves treatment responsiveness in animal models of high-risk B-ALL.

from Cancer Cell https://ift.tt/2ZKkVO7
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