Using a generalizable framework to leverage single-cell chromatin accessibility data to investigate cell state transitions across tumor evolution in a mouse model of lung adenocarcinoma, LaFave et al. elucidate a pre-metastatic cell state that arises in primary tumors prior to metastasis.
from Cancer Cell https://ift.tt/3js9MJj
from Cancer Cell https://ift.tt/3js9MJj