Zhao et al. profile the protein responses of a large collection of cancer cell lines to drug perturbations using the RPPA platform and build a systematic protein-drug connectivity map. The integration of perturbed protein responses provides better prediction of drug sensitivity and insights into drug-resistance mechanisms and combination therapies.
from Cancer Cell https://ift.tt/2Gv1Xnm
from Cancer Cell https://ift.tt/2Gv1Xnm