PRC2 Plays Red Light, Green Light with MHC-I and CD8+ T Cells

In this issue of Cancer Cell, Burr et al. report that PRC2 plays a conserved role in silencing antigen presentation and processing genes and, in turn, CD8+ T cell activation. Furthermore, PRC2-targeted therapeutics overcome gene silencing and promote tumor clearance by cytotoxic T cells.

from Cancer Cell https://ift.tt/2MhThkB