Cheung et al. show that TIGAR expression is dynamically regulated during the development of pancreatic ductal adenocarcinoma, resulting in lower levels of ROS to promote tumor initiation in the premalignant condition and higher levels of ROS that enable metastatic progression.
from Cancer Cell https://ift.tt/2uw3LGf
from Cancer Cell https://ift.tt/2uw3LGf