Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells

Using a combination of pre-clinical models and phosphoproteomics, Coles et al. identify protein kinase A (PKA) and molecules in the PKA signaling pathway as key regulators of small cell lung cancer initiation and progression.

from Cancer Cell https://ift.tt/3cRtwRZ