Lymph nodes are typically the first clinically detectable site of metastasis in melanoma, but the mechanisms that determine this preference are not well understood. An article in Nature reports that the unique composition of lymph may protect melanoma cells from ferroptosis—a form of iron-dependent cell death, thereby increasing metastatic efficiency.
from Cancer Cell https://ift.tt/2ZoqyR7
from Cancer Cell https://ift.tt/2ZoqyR7