Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade

Motzer et al. perform integrative multi-omics analyses of 823 renal cancer tumors from a randomized clinical trial. A robust molecular classification scheme, based on transcriptional and gene alteration profiles and differential clinical outcomes to VEGF blockade alone or in combination with anti-PD-L1, informs personalized treatment strategies and future therapeutic development in RCC.

from Cancer Cell https://ift.tt/34Y3tru
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