Guccini et al. show that TIMP1 loss switches senescence from a tumor-suppressive to a pro-metastatic process in prostate cancer mouse models. Pharmacological targeting of TIMP1-deficient senescent tumor cells impedes metastases i…
Han et al. show that CXorf67 interacts with PALB2 and obstructs the PALB2-BRCA2 interaction, thereby inhibiting homologous recombination repair. A combination of PARP inhibitors with radiotherapy could be an effective treatment o…
Language English November 12, 2020 Brielle.Gregory Dr. William Dale discusses 5 key studies presented at the SIOG 2020 Annual Meeting Online that involve improvements in evaluating, caring for, and treating pe…
For children with the eye cancer retinoblastoma, researchers are studying a CAR T-cell therapy in which the engineered immune cells are packaged in a biodegradable material called a hydrogel and then injected directly into tumors…
Language English November 10, 2020 Narjust.Duma In this post, Dr. Narjust Duma discusses the unique challenges people living with and beyond lung cancer face in terms of their sexual health, and how they can b…
Language English November 9, 2020 Brielle.Gregory In this podcast, 3 experts discuss what it means to have the capacity to make decisions during cancer, and what families and caregivers should know if they nee…
The age at which people tend to start smoking has shifted upwards, with more young adults than teens trying smoking for the first time or becoming regular smokers, according to a new study. from Cancer Currents: An NCI Cancer R…